Publications

Two Decades of

Translational Research

We don’t just innovate — we validate. Our technologies are the result of two decades of translational research in:

Stem Cell Biology

Oral Mucosal Tissue Nutrient Restoration

Soft Tissue Nourishment

Bioactive Mineral Therapies

Selected Publications

  1. Al Madhoun, A., Meshal, K., Carrió, N., Ferrés-Amat, E., Ferrés-Amat, E., Barajas, M., Jiménez-Escobar, A. L., Al-Madhoun, A. S., Saber, A., Abou Alsamen, Y., Marti, C., & Atari, M. (2024). Randomized Clinical Trial: Bone Bioactive Liquid Improves Implant Stability and Osseointegration. Journal of functional biomaterials, 15(10), 293. https://doi.org/10.3390/jfb15100293

  2. Ferrés-Amat, E., Al Madhoun, A., Ferrés-Amat, E., Carrió, N., Barajas, M., Al-Madhoun, A. S., Ferrés-Padró, E., Marti, C., & Atari, M. (2022). Comparison of 0.12% Chlorhexidine and a New Bone Bioactive Liquid, BBL, in Mouthwash for Oral Wound Healing: A Randomized, Double Blind Clinical Human Trial. Journal of personalized medicine, 12(10), 1725. https://doi.org/10.3390/jpm12101725

  3. Al Madhoun, A., Meshal, K., Carrió, N., Ferrés-Amat, E., Ferrés-Amat, E., Barajas, M., Jiménez-Escobar, A. L., Al-Madhoun, A. S., Saber, A., Abou Alsamen, Y., Marti, C., & Atari, M. (2024). Randomized Clinical Trial: Bone Bioactive Liquid Improves Implant Stability and Osseointegration. Journal of functional biomaterials, 15(10), 293. https://doi.org/10.3390/jfb15100293

  4. Al Madhoun, A., Koti, L., Carrió, N., Atari, M., & Al-Mulla, F. (2024). Clinical Application of Umbilical Cord Mesenchymal Stem Cells Preserves β-cells in Type 1 Diabetes. Stem cells translational medicine, 13(2), 101–106. https://doi.org/10.1093/stcltm/szad077

  5. Gil-Recio, C., Montori, S., Al Demour, S., Ababneh, M. A., Ferrés-Padró, E., Marti, C., Ferrés-Amat, E., Barajas, M., Al Madhoun, A., & Atari, M. (2021). Chemically Defined Conditions Mediate an Efficient Induction of Dental Pulp Pluripotent-Like Stem Cells into Hepatocyte-Like Cells. Stem cells international, 2021, 5212852. https://doi.org/10.1155/2021/5212852

  6. Martínez-Sarrà, E., Montori, S., Gil-Recio, C., Núñez-Toldrà, R., Costamagna, D., Rotini, A., Atari, M., Luttun, A., & Sampaolesi, M. (2017). Human dental pulp pluripotent-like stem cells promote wound healing and muscle regeneration. Stem cell research & therapy, 8(1), 175. https://doi.org/10.1186/s13287-017-0621-3

  7. Núñez-Toldrà, R., Dosta, P., Montori, S., Ramos, V., Atari, M., & Borrós, S. (2017). Improvement of osteogenesis in dental pulp pluripotent-like stem cells by oligopeptide-modified poly(β-amino ester)s. Acta biomaterialia, 53, 152–164. https://doi.org/10.1016/j.actbio.2017.01.077

  8. Atari, M., Gil-Recio, C., Fabregat, M., García-Fernández, D., Barajas, M., Carrasco, M. A., Jung, H. S., Alfaro, F. H., Casals, N., Prosper, F., Ferrés-Padró, E., & Giner, L. (2012). Dental pulp of the third molar: a new source of pluripotent-like stem cells. Journal of cell science, 125(Pt 14), 3343–3356. https://doi.org/10.1242/jcs.096537

  9. Ferrés-Amat, E., Al Madhoun, A., Ferrés-Amat, E., Al Demour, S., Ababneh, M. A., Ferrés-Padró, E., Marti, C., Carrio, N., Barajas, M., & Atari, M. (2021). Histologic and Histomorphometric Evaluation of a New Bioactive Liquid BBL on Implant Surface: A Preclinical Study in Foxhound Dogs. Materials (Basel, Switzerland), 14(20), 6217. https://doi.org/10.3390/

  10. Al Madhoun, A., Alkandari, S., Ali, H., Carrio, N., Atari, M., Bitar, M. S., & Al-Mulla, F. (2018). Chemically Defined Conditions Mediate an Efficient Induction of Mesodermal Lineage from Human Umbilical Cord- and Bone Marrow- Mesenchymal Stem Cells and Dental Pulp Pluripotent-Like Stem Cells. Cellular reprogramming, 20(1), 9–16. https://doi.org/10.1089/cell.2017.0028

  11. Núñez-Toldrà, R., Montori, S., Bosch, B., Hupa, L., Atari, M., & Miettinen, S. (2019). S53P4 Bioactive Glass Inorganic Ions for Vascularized Bone Tissue Engineering by Dental Pulp Pluripotent-Like Stem Cell Cocultures. Tissue engineering. Part A, 25(17-18), 1213–1224. https://doi.org/10.1089/ten.TEA.2018.0256

  12. Al Madhoun, A., Marafie, S. K., Haddad, D., Melhem, M., Abu-Farha, M., Ali, H., Sindhu, S., Atari, M., & Al-Mulla, F. (2020). Comparative Proteomic Analysis Identifies EphA2 as a Specific Cell Surface Marker for Wharton’s Jelly-Derived Mesenchymal Stem Cells. International journal of molecular sciences, 21(17), 6437. https://doi.org/10.3390/ijms21176437\

  13. Núñez-Toldrà, R., Martínez-Sarrà, E., Gil-Recio, C., Carrasco, M. Á., Al Madhoun, A., Montori, S., & Atari, M. (2017). Dental pulp pluripotent-like stem cells (DPPSC), a new stem cell population with chromosomal stability and osteogenic capacity for biomaterials evaluation. BMC cell biology, 18(1), 21. https://doi.org/10.1186/s12860-017-0137-9

  14. Al Madhoun, A., Ali, H., AlKandari, S., Atizado, V. L., Akhter, N., Al-Mulla, F., & Atari, M. (2016). Defined three-dimensional culture conditions mediate efficient induction of definitive endoderm lineage from human umbilical cord Wharton’s jelly mesenchymal stem cells. Stem cell research & therapy, 7(1), 165. https://doi.org/10.1186/s13287-016-0426-9

  15. Maher, A., Núñez-Toldrà, R., Carrio, N., Ferres-Padro, E., Ali, H., Montori, S., & Al Madhoun, A. (2018). The Effect of Commercially Available Endodontic Cements and Biomaterials on Osteogenic Differentiation of Dental Pulp Pluripotent-Like Stem Cells. Dentistry journal, 6(4), 48. https://doi.org/10.3390/dj6040048

  16. Porciuncula, A., Kumar, A., Rodriguez, S., Atari, M., Araña, M., Martin, F., Soria, B., Prosper, F., Verfaillie, C., & Barajas, M. (2016). Pancreatic differentiation of Pdx1-GFP reporter mouse induced pluripotent stem cells. Differentiation; research in biological diversity, 92(5), 249–256. https://doi.org/10.1016/j.diff.2016.04.005

  17. Porciuncula, A., Kumar, A., Rodriguez, S., Atari, M., Araña, M., Martin, F., Soria, B., Prosper, F., Verfaillie, C., & Barajas, M. (2016). Pancreatic differentiation of Pdx1-GFP reporter mouse induced pluripotent stem cells. Differentiation; research in biological diversity, 92(5), 249–256. https://doi.org/10.1016/j.diff.2016.04.005

  18. Roa-Mansergas, X., Fadó, R., Atari, M., Mir, J. F., Muley, H., Serra, D., & Casals, N. (2018). CPT1C promotes human mesenchymal stem cells survival under glucose deprivation through the modulation of autophagy. Scientific reports, 8(1), 6997. https://doi.org/10.1038/s41598-018-25485-7

  19. Porciuncula, A., Kumar, A., Rodriguez, S., Atari, M., Araña, M., Martin, F., Soria, B., Prosper, F., Verfaillie, C., & Barajas, M. (2016). Pancreatic differentiation of Pdx1-GFP reporter mouse induced pluripotent stem cells. Differentiation; research in biological diversity, 92(5), 249–256. https://doi.org/10.1016/j.diff.2016.04.005

  20. Al Madhoun A, Sindhu S, Haddad D, Atari M, Ahmad R, Al-Mulla F. Dental Pulp Stem Cells Derived From Adult Human Third Molar Tooth: A Brief Review. Front Cell Dev Biol. 2021 Oct 12;9:717624. doi: 10.3389/fcell.2021.717624. PMID: 34712658; PMCID: PMC8545885.

  21. Arana, M., Kumar, A., Ashwathnarayan, A., Atari, M., & Barajas, M. (2018). Type 1 Diabetes Treatments Based on Stem Cells. Current diabetes reviews, 14(1), 14–23. https://doi.org/10.2174/1573399813666170609100219
Access HCP Real-World Evidence